【Holy Joe】 —(Nautical) a parson; a devoutly religious person:
They all have these 【Holy Joe】 voices when they start giving their sermons.
【Holy Willie】 —a hypocritically pious person:
The Holy Willies were just like the slave-owners who outlawed traditional African religions.
Note: Neither expression correlates in meaning with the phrase Holy Moses—(exclam.) used to express strong feelings of astonishment, pleasure, or anger:
Copland was astonished to see things he had not looked at for over sixty years. “Holy Moses!” he exclaimed, “I kept everything!”