【Empty】 ,  【vacant】 ,  【blank】 ,  【void】 ,  【vacuous】  mean lacking the contents that could or should be present.

Something is  【empty】  which has nothing in it; something is  【vacant】 which is without an occupant, incumbent, tenant, inmate, or the person or thing it appropriately contains.

When qualifying the same nouns the words usually suggest distinctly different ideas; thus, an  【empty】  house has neither furniture nor occupants; a  【vacant】  house is without inmates and presumably for rent or for sale; an  【empty】  chair has no one sitting in it at the time; a  【vacant】  chair is one that has lost its usual occupant by death or other cause; an  【empty】  space has nothing in it; a  【vacant】 space is one left to be filled with what is appropriate.

Something, especially a surface, is  【blank】 which is free from writing or marks or which has 【vacant】 spaces that are left to be filled in.

Something is  【void】 which is absolutely 【empty】 so far as the senses can discover.

Something is  【vacuous】 which exhibits the absolute emptiness of a vacuum.

In extended use the same distinctions hold: an  【empty】  mind is destitute of worthwhile ideas or knowledge; a  【vacant】  mind lacks its usual occupant, the soul or intellect; a  【blank】  look is without expression; a person is said to be  【void】  of learning or of common sense when not the slightest evidence of either one can be detected; a  【vacuous】 mind, look, or expression is so deficient in alertness or spirit as to suggest a vacuum in its inanity.