【Effect】 ,  【result】 ,  【consequence】 ,  【upshot】 ,  【aftereffect】 ,  【aftermath】 ,  【sequel】 ,  【issue】 ,  【outcome】 ,  【event】  are comparable in signifying something, usually a condition, situation, or occurrence, ascribable to a cause or combination of causes.

【Effect】  is the correlative of the word cause and in general use implies something (as a bodily or social condition or a state of mind) necessarily and directly following upon or occurring by reason of a cause.

【Result】 , close to  【effect】  in meaning, implies a direct relationship with an antecedent action or condition, usually suggests an 【effect】 that terminates the operation of a cause, and applies more commonly than  【effect】 to tangible objects.

【Consequence】  may suggest a direct but looser or more remote connection with a cause than either  【effect】  or  【result】 , sometimes implying an adverse or calamitous 【effect】 and often suggesting a chain of intermediate causes or a complexity of 【effect】 .

【Upshot】 often implies a climax or conclusion in a series of consequent occurrences or the most conclusive point of a single complex gradual 【consequence】 .

【Aftereffect】  and  【aftermath】  both usually designate secondary rather than direct or immediate effects.

【Aftereffect】 besides designating a secondary 【effect】 sometimes suggests a side 【effect】 but more generally implies an 【effect】 ascribable to a previous 【effect】 that has become a cause.

【Aftermath】  often suggests a more complex 【effect】 or generalized condition than  【aftereffect】 and usually carries the notion of belated consequences that appear after the effects, especially disastrous effects, seem to have passed.

【Sequel】 usually signifies a 【result】 that follows after an interval.

【Issue】  adds to  【result】 the implication of exit or escape (as from difficulties); it therefore usually designates a 【result】 that is a solution or a resolution.

【Outcome】 , though often interchangeable with  【result】  or  【issue】 , may put less stress on the notion of finality than does  【issue】 .

【Event】 , which is both uncommon and somewhat archaic in this relation, usually carries the notion of an unpredictable or unforeseeable 【outcome】 and comes very close to the related eventuality in its implication of a possible or contingent 【effect】 or 【result】 .