【Cynical】 , 【misanthropic】 , 【pessimistic】 , 【misogynie】 are comparable when meaning deeply and often contemptuously distrustful.
【Cynical】 implies a sneering disbelief in sincerity and integrity.
【Misanthropic】 implies a rooted dislike and distrust of one’s fellowmen and aversion to their society.
【Pessimistic】 suggests a distrustful and gloomy view of things in general.
【Misogynie】 implies a deep-seated aversion to, and a profound distrust of, women.