1. 1. loss of the ability of a muscle to respond to stimuli.
2. a nursing diagnosis accepted by the North American Nursing Diagnosis Association, defined as an overwhelming sustained exhaustion and decreased capacity for physical and mental work at the usual level. Fatigue is a normal reaction to intense physical exertion, emotional strain, or lack of rest. When it is not relieved by rest, it may have a more serious origin; it may be a symptom of poor physical condition, a specific disease or oncoming disease, or severe emotional stress. Sometimes fatigue is psychological in origin. Tiredness and a loss of interest in one's work may actually result from boredom with the daily routine. If one is certain that there is nothing wrong physically, steps should be taken to vary the daily round, to seek new and more active ways to spend leisure time, perhaps to revive old interests that have been neglected. See also activity intolerance .
caregiver role fatigue excessive fatigue of a caregiver caused by the neglect of his or her personal needs due to the demands of physical and emotional care of someone else.
vocal fatigue phonasthenia .